Fat Hormone Increases Risk of Dementia in Women

Tue, 03 Jan 2012
New research suggests that a fat hormone in body fat could contribute towards a higher risk of dementia and Alzheimer's disease (AD) in women.

AD is the most usual kind of dementia. The researchers suggest a link between insulin resistance and inflammation, signpost or type 2 diabetes and the development of dementia.

The researchers have confirmed that another possible factor which can contribute to the onset of AD and all-cause dementia is adiponectin.

Adiponectin is a hormone which is derived from visceral fat. It sensitises the body to insulin and has anti-inflammatory properties. It also plays a pivotal role in the metabolism of glucose and lipids.

840 patients of whom 541 were women, were monitored for 13 years and signs of the development of AD and all-cause dementia were evaluated.

During this period, 159 patients got dementia, including 125 cases of AD.

Upon taking into account other dementia risk factors just adiponectin in women was related to an increased risk of all-cause dementia and AD.

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